| 141 | SEKISUI DLJM MOLDING PVT LTD | Kanchipuram | Private Limited | Polymer | Product | Process | CH | EE | ME | AU | RA | 60 | 15300 | | |
| 142 | Seonex Power solution | Kothanalloor | Sole Proprietorship | Electrical | Product | EE | EL | 4 | 8000 | | |
| 143 | SFO Technologies Pvt Ltd | Kochi | Private Limited | Electronics | Product | EE | EL | ME | 250 | 8000 | | |
| 144 | Sharada Motor Industries Limited | Mahindra World City | Private Limited | Mechanical | Product | ME | IE | AU | RA | MC | OT | 200 | 17500 | | |
| 145 | Silpi Architects Pvt Ltd | Thevara | Private Limited | Civil | Service | CE | 5 | 8000 | | |
| 146 | Simak builders | Kondotty | Private Limited | Civil | Service | CE | AR | 10 | 8000 | | |
| 147 | SIRIUS ENGINEERING PRIVATE LIMITED | COIMBATORE | Private Limited | Mechanical | Product | Process | ME | 30 | 10000 | | |
| 148 | Sketis group | Thalappara | Partnerships | Civil | Service | CE | 5 | 12000 | | |
| 149 | SMEC AUTOMATION PRIVATE LIMITED | Cochin | Private Limited | Electrical | Product | Process | Service | CE | CB | CT | EE | EL | ME | IE | AU | AR | RA | AM | MC | 100 | 10000 | | |
| 150 | SPECTRUM BIOMEDICAL SERVICES | thiruvankulam | Sole Proprietorship | Other | Product | Service | BM | 2 | 8000 | | |
| 151 | Steel Strips Wheels Limited | Oragadam | Public Limited | Mechanical | Product | CE | ME | AU | RA | MC | 150 | 20000 | | |
| 152 | Streparava India Private Limited | Bangalore | Private Limited | Mechanical | Product | ME | AU | 25 | 19666 | | |
| 153 | Technoflex Rubber Products | Perumbavoor | Partnerships | Polymer | Product | ME | OT | 4 | 8000 | | |
| 154 | Tenneco Clean Air India limited | CHENNAI | Private Limited | Mechanical | Product | EE | ME | IE | AU | RA | MC | 150 | 19000 | | |
| 155 | thrissur home designers | KODAKARA | Sole Proprietorship | Civil | Service | CE | 25 | 8000 | | |
| 156 | Tolins Tyres Limited | Kalady | Public Limited | Other | Product | EE | ME | OT | 10 | 12000 | | |
| 157 | Transenergy Private Limited | CHENNAI | Private Limited | Mechanical | Product | EE | EL | ME | AU | RA | MC | 250 | 14000 | | |
| 158 | TRYCODE INNOVATIONS | ARAYIDATHUPALAM | Partnerships | Computer/IT | Service | CB | CT | EL | AM | 20 | 8000 | | |
| 159 | TVS Sundram Fasteners Limited , Autolec Division | Chennai | Public Limited | Mechanical | Product | Process | EE | ME | IE | AU | RA | MC | OT | 200 | 18000 | | |
| 160 | TVS Sundram Fasteners Limited , Autolec Division, Plant 3 | Chennai | Public Limited | Mechanical | Product | Process | EE | EL | ME | IE | AU | RA | MC | OT | 150 | 18000 | | |